Proteomic analysis of sputum in patients with active pulmonary tuberculosis.

  title={Proteomic analysis of sputum in patients with active pulmonary tuberculosis.},
  author={Yu-rong Fu and Zhang Jing Yi and Shuang Guan and Shao-yang Zhang and Meng Li},
  journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases},
  volume={18 12},
The protein composition of sputum most faithfully reflects the state of the lungs. The aim of this study was to determine whether relative qualitative and quantitative differences in protein expression of sputum could be related to active pulmonary tuberculosis. Sputum samples were collected from 65 patients with active pulmonary tuberculosis and 38 healthy controls. Comprehensive proteomic approaches were used to profile the proteome changes of host sputum in response to Mycobacterium… CONTINUE READING
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