Proteomic analysis of slow- and fast-twitch skeletal muscles.

  title={Proteomic analysis of slow- and fast-twitch skeletal muscles.},
  author={Nobuaki Okumura and Akiko Hashida-Okumura and Kanako Kita and Masami Matsubae and Toshiya Matsubara and Toshifumi Takao and Katsuya Nagai},
  volume={5 11},
Skeletal muscles are composed of slow- and fast-twitch muscle fibers, which have high potential in aerobic and anaerobic ATP production, respectively. To investigate the molecular basis of the difference in their functions, we examined protein profiles of skeletal muscles using sodium dodecyl sulfate-polyacrylamide gel electrophoresis and two-dimensional gel electrophoresis with pH 4-7 and 6-11 isoelectric focusing gels. A comparison between rat soleus and extensol digitorum longus (EDL… CONTINUE READING