Proteomic analysis of outer membrane vesicles from the probiotic strain Escherichia coli Nissle 1917

@article{Aguilera2014ProteomicAO,
  title={Proteomic analysis of outer membrane vesicles from the probiotic strain Escherichia coli Nissle 1917},
  author={L. Aguilera and L. Toloza and R. Giménez and Antonia Odena and E. Oliveira and J. Aguilar and J. Badía and L. Baldom{\`a}},
  journal={PROTEOMICS},
  year={2014},
  volume={14}
}
Escherichia coli Nissle 1917 (EcN) is a probiotic used for the treatment of intestinal disorders. EcN improves gastrointestinal homeostasis and microbiota balance; however, little is known about how this probiotic delivers effector molecules to the host. Outer membrane vesicles (OMVs) are constitutively produced by Gram‐negative bacteria and have a relevant role in bacteria–host interactions. Using 1D SDS–PAGE and highly sensitive LC–MS/MS analysis we identified in this study 192 EcN vesicular… Expand
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