Proteomic analysis of nipple aspirate fluid to detect biologic markers of breast cancer

@article{Sauter2002ProteomicAO,
  title={Proteomic analysis of nipple aspirate fluid to detect biologic markers of breast cancer},
  author={Edward R Sauter and Wu Zhu and X-J Fan and Richard P Wassell and Inna Chervoneva and G C Du Bois},
  journal={British Journal of Cancer},
  year={2002},
  volume={86},
  pages={1440 - 1443}
}
The early detection of breast cancer is the best means to minimise disease-related mortality. Current screening techniques have limited sensitivity and specificity. Breast nipple aspirate fluid can be obtained noninvasively and contains proteins secreted from ductal and lobular epithelia. Nipple aspirate fluid proteins are breast specific and generally more concentrated than corresponding blood levels. Proteomic analysis of 1 μl of diluted nipple aspirate fluid over a 5–40 kDa range from 20… CONTINUE READING