Proteomic analysis of individual human embryos to identify novel biomarkers of development and viability.

@article{KatzJaffe2006ProteomicAO,
  title={Proteomic analysis of individual human embryos to identify novel biomarkers of development and viability.},
  author={Mandy G. Katz-Jaffe and David K Gardner and William B. Schoolcraft},
  journal={Fertility and sterility},
  year={2006},
  volume={85 1},
  pages={101-7}
}
OBJECTIVE To develop a method to analyze the proteome of individual human blastocysts and identify differentially expressed proteins prior to implantation. DESIGN Experimental study. SETTING Research environment. PATIENT(S) Couples undergoing infertility treatment donated with consent cryopreserved human cleavage-stage embryos for research. INTERVENTION(S) Individual embryos were extracted and analyzed by time-of-flight mass spectrometry. MAIN OUTCOME MEASURE(S) The protein expression… CONTINUE READING

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