Proteomic analysis of human omental adipose tissue in the polycystic ovary syndrome using two-dimensional difference gel electrophoresis and mass spectrometry.

@article{Corton2008ProteomicAO,
  title={Proteomic analysis of human omental adipose tissue in the polycystic ovary syndrome using two-dimensional difference gel electrophoresis and mass spectrometry.},
  author={M. Corton and J. Botella-Carretero and J. A. L{\'o}pez and E. Camafeita and J. S. San Mill{\'a}n and H. Escobar-Morreale and B. Peral},
  journal={Human reproduction},
  year={2008},
  volume={23 3},
  pages={
          651-61
        }
}
BACKGROUND Our aim was to study the protein expression profiles of omental adipose tissue biopsies obtained from morbidly obese women with or without polycystic ovary syndrome (PCOS) at the time of bariatric surgery to evaluate the possible involvement of visceral adiposity in the development of PCOS. METHODS Ten PCOS patients and nine control samples were included. We used two-dimensional difference gel electrophoresis (2D-DIGE) followed by in-gel digestion, and mass spectrometry (MS) of… Expand
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