Proteomic analysis of cytokine induced proteins in human intestinal epithelial cells: implications for inflammatory bowel diseases.

@article{BarcelBatllori2002ProteomicAO,
  title={Proteomic analysis of cytokine induced proteins in human intestinal epithelial cells: implications for inflammatory bowel diseases.},
  author={S{\'i}lvia Barcel{\'o}-Batllori and Muriel Andr{\'e} and Catherine Servis and Nicole L{\'e}vy and Osamu Takikawa and P Michetti and Marc Andr{\'e} Reymond and Emanuela Felley-Bosco},
  journal={Proteomics},
  year={2002},
  volume={2 5},
  pages={551-60}
}
A role for cytokine regulated proteins in epithelial cells has been suggested in the pathogenesis of inflammatory bowel diseases (IBD). The aim of this study was to identify such cytokine regulated targets using a proteomic functional approach. Protein patterns from (35)S-radiolabeled homogenates of cultured colon epithelial cells were compared before and after exposure to interferon-gamma, interleukin-1beta and interleukin-6. Proteins were separated by two-dimensional polyacrylamide gel… CONTINUE READING