Proteomic analysis of brain plasma membranes isolated by affinity two-phase partitioning.

@article{Schindler2006ProteomicAO,
  title={Proteomic analysis of brain plasma membranes isolated by affinity two-phase partitioning.},
  author={Jens Schindler and Urs Lewandrowski and Albert Sickmann and Eckhard Friauf and Hans Gerd Nothwang},
  journal={Molecular & cellular proteomics : MCP},
  year={2006},
  volume={5 2},
  pages={390-400}
}
A comprehensive analysis of plasma membrane proteins is essential to in-depth understanding of brain development, function, and diseases. Proteomics offers the potential to perform such a comprehensive analysis, yet it requires efficient protocols for the purification of the plasma membrane compartment. Here, we present a novel and efficient protocol for the separation and enrichment of brain plasma membrane proteins. It lasts only 4 h and is easy to perform. It highly enriches plasma membrane… CONTINUE READING