Proteomic analysis of anoxia tolerance in the developing zebrafish embryo.

@article{Mendelsohn2009ProteomicAO,
  title={Proteomic analysis of anoxia tolerance in the developing zebrafish embryo.},
  author={Bryce A. Mendelsohn and James P. Malone and R. Reid Townsend and Jonathan D. Gitlin},
  journal={Comparative biochemistry and physiology. Part D, Genomics & proteomics},
  year={2009},
  volume={4 1},
  pages={21-31}
}
While some species and tissue types are injured by oxygen deprivation, anoxia tolerant organisms display a protective response that has not been fully elucidated and is well-suited to genomic and proteomic analysis. However, such methodologies have focused on transcriptional responses, prolonged anoxia, or have used cultured cells or isolated tissues. In this study of intact zebrafish embryos, a species capable of >24 h survival in anoxia, we have utilized 2D difference in gel electrophoresis… CONTINUE READING

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