Proteomic analysis of a model fish species exposed to individual pesticides and a binary mixture.

  title={Proteomic analysis of a model fish species exposed to individual pesticides and a binary mixture.},
  author={Adam D. Biales and David C. Bencic and Robert L Flick and Karen A. Blocksom and James M. Lazorchak and David L Lattier},
  journal={Aquatic toxicology},
  volume={101 1},
Pesticides are nearly ubiquitous in surface waters of the United States, where they often are found as mixtures. The molecular mechanisms underlying the toxic effects of sub-lethal exposure to pesticides as both individual and mixtures are unclear. The current work aims to identify and compare differentially expressed proteins in brains of male fathead minnows (Pimephales promelas) exposed for 72 h to permethrin (7.5 μg/L), terbufos (57.5 μg/L) and a binary mixture of both. Twenty-four proteins… CONTINUE READING


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