Proteomic analysis of Tityus discrepans scorpion venom and amino acid sequence of novel toxins.

@article{Batista2006ProteomicAO,
  title={Proteomic analysis of Tityus discrepans scorpion venom and amino acid sequence of novel toxins.},
  author={Cesar Vicente Ferreira Batista and Gina D'suze and Froylan G{\'o}mez-Lagunas and Fernando Z. Zamudio and Sergio Encarnaci{\'o}n and Carlos Sevcik and Lourival Domingos Possani},
  journal={Proteomics},
  year={2006},
  volume={6 12},
  pages={3718-27}
}
The Venezuelan scorpion Tityus discrepans is known to cause human fatalities. We describe the first complete proteomic analysis of its venom. By HPLC 58 different fractions were obtained and 205 different components were identified by MS analysis. Components having molecular masses from 272 to 57 908 amu were found. Forty homogeneous components had their N-terminal amino acid sequence determined by Edman degradation, from which two new peptides named TdK2 and TdK3 (meaning T. discrepans (Td) K… CONTINUE READING
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