Proteomic analysis of Rac1 transgenic mice displaying dilated cardiomyopathy reveals an increase in creatine kinase M-chain protein abundance

@article{Buscemi2003ProteomicAO,
  title={Proteomic analysis of Rac1 transgenic mice displaying dilated cardiomyopathy reveals an increase in creatine kinase M-chain protein abundance},
  author={Nina Buscemi and Amanda L. Doherty-Kirby and Mark A Sussman and G. Lajoie and Jennifer E. Van Eyk},
  journal={Molecular and Cellular Biochemistry},
  year={2003},
  volume={251},
  pages={145-151}
}
Here, we demonstrate the application of the proteomic approach to the study of a transgenic mouse model of heart failure and provide an example of a disease-associated protein alteration that can be observed using this approach. Specifically, we applied the proteomic approach to the analysis of a mouse model of dilated cardiomyopathy in which the small… CONTINUE READING