Proteomic analysis of Down's syndrome patients with gout.

  title={Proteomic analysis of Down's syndrome patients with gout.},
  author={Ying-Chou Chen and Pei-wen Wang and Tai-Long Pan and Christopher Glenn Wallace and Chung-Jen Chen},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  volume={369 1},
BACKGROUND In this study, the expression of hypoxanthine-guanine phosphoribosyl transferase (HPRT) in Down's syndrome patients with gout (DS/G) was determined, and possible underlying mechanisms of gout were characterized using proteomic tools. METHODS Serum was obtained from DS/G, healthy controls and gout patients (without DS), recruited from the… CONTINUE READING