Proteomic analysis in lung tissue of smokers and COPD patients.

  title={Proteomic analysis in lung tissue of smokers and COPD patients.},
  author={Eun Joo Lee and Kwang Ho In and Je Hyeong Kim and Sang Yeub Lee and Chol Shin and Jae Jeong Shim and Kyung Ho Kang and Se Hwa Yoo and Chul Hwan Kim and Han-Kyeom Kim and Sang Hoon Lee and Chang Sub Uhm},
  volume={135 2},
RATIONALE Although cigarette smoking is the most important risk factor for COPD, COPD develops in only a minority of smokers, suggesting a significant genetic role. To solve the underlying pathophysiologic mechanism, it is critical to understand genes and their final product, ie, proteins. We investigated the exclusive proteins from the lung tissues obtained from COPD patients using proteomics. METHODS Nontumorous lung tissue specimens were obtained from patients who underwent surgery for… CONTINUE READING


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