Proteomic analysis identifies a new complex required for nuclear pre-mRNA retention and splicing.

@article{Dziembowski2004ProteomicAI,
  title={Proteomic analysis identifies a new complex required for nuclear pre-mRNA retention and splicing.},
  author={Andrzej Dziembowski and Ana-Paula Ventura and Berthold Rutz and Friederike Caspary and C{\'e}line Faux and Fr{\'e}d{\'e}ric Halgand and Olivier Lapr{\'e}v{\^o}te and Bertrand S{\'e}raphin},
  journal={The EMBO journal},
  year={2004},
  volume={23 24},
  pages={4847-56}
}
Using the proteomic tandem affinity purification (TAP) method, we have purified the Saccharomyces cerevisie U2 snRNP-associated splicing factors SF3a and SF3b. While SF3a purification revealed only the expected subunits Prp9p, Prp11p and Prp21p, yeast SF3b was found to contain only six subunits, including previously known components (Rse1p, Hsh155p, Cus1p, Hsh49p), the recently identified Rds3p factor and a new small essential protein (Ysf3p) encoded by an unpredicted split ORF in the yeast… CONTINUE READING
Highly Influential
This paper has highly influenced 11 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
71 Citations
59 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 71 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 59 references

Similar Papers

Loading similar papers…