Proteomic analysis for antiobesity potential of capsaicin on white adipose tissue in rats fed with a high fat diet.

@article{Joo2010ProteomicAF,
  title={Proteomic analysis for antiobesity potential of capsaicin on white adipose tissue in rats fed with a high fat diet.},
  author={Jeong In Joo and Dong Hyun Kim and Jung-Won Choi and Jong Won Yun},
  journal={Journal of proteome research},
  year={2010},
  volume={9 6},
  pages={2977-87}
}
It is well recognized that capsaicin increases thermogenesis through enhancement of catecholamine secretion from the adrenal medulla. In the present study of the antiobesity effect of capsaicin, rats (5-week old) received capsaicin (10 mg/kg) along with a high-fat diet (HFD). In comparison with saline-treated rats, body weight of those in the capsaicin-treated group decreased by 8%. We performed differential proteomic analysis using two-dimensional electrophoresis (2-DE) combined with MALDI-TOF… CONTINUE READING
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