Proteomic analysis demonstrates adolescent vulnerability to lasting hippocampal changes following chronic alcohol consumption.

@article{Hargreaves2009ProteomicAD,
  title={Proteomic analysis demonstrates adolescent vulnerability to lasting hippocampal changes following chronic alcohol consumption.},
  author={Garth A. Hargreaves and Heidi S. Quinn and Mohammed Abul Kashem and Izuru Matsumoto and Iain S McGregor},
  journal={Alcoholism, clinical and experimental research},
  year={2009},
  volume={33 1},
  pages={
          86-94
        }
}
BACKGROUND Excessive teenage alcohol consumption is of great concern because alcohol may adversely alter the developmental trajectory of the brain. The aim of the present study was to assess whether chronic intermittent alcohol intake during the adolescent period alters hippocampal protein expression to a greater extent than during adulthood. METHODS Adolescent [postnatal day (PND) 27] and adult (PND 55) male Wistar rats were given 8 hours daily access to beer (4.44% ethanol v/v) in addition… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 20 CITATIONS

Similar Papers

Loading similar papers…