Proteomic analysis and quantification of cytokines and chemokines from biomaterial surface-adherent macrophages and foreign body giant cells.

@article{Jones2007ProteomicAA,
  title={Proteomic analysis and quantification of cytokines and chemokines from biomaterial surface-adherent macrophages and foreign body giant cells.},
  author={Jacqueline A Jones and David T. Chang and Howard Meyerson and Erica Colton and Il Keun Kwon and Takehisa Matsuda and James M Anderson},
  journal={Journal of biomedical materials research. Part A},
  year={2007},
  volume={83 3},
  pages={585-96}
}
Implantation of biomaterial devices results in the well-known foreign body reaction consisting of monocytes, macrophages, and foreign body giant cells (FBGCs) at the material/tissue interface. We continue to address the hypothesis that material surface chemistry modulates the phenotypic expression of these cells. Utilizing our human monocyte culture system, we have used surface-modified polymers displaying hydrophobic, hydrophilic, and/or ionic chemistries to determine the cytokines/chemokines… CONTINUE READING
75 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 75 extracted citations

Similar Papers

Loading similar papers…