Proteomic analyses of serous and endometrioid epithelial ovarian cancers - cases studies - molecular insights of a possible histological etiology of serous ovarian cancer.

@article{Longuespe2013ProteomicAO,
  title={Proteomic analyses of serous and endometrioid epithelial ovarian cancers - cases studies - molecular insights of a possible histological etiology of serous ovarian cancer.},
  author={R{\'e}mi Longuesp{\'e}e and Hugo Gagnon and Charlotte Boyon and Kurstin Strupat and Claire Dauly and Olivier Kerdraon and Adesuwa Ighodaro and Annie Desmons and Jocelyn Dupuis and Maxence Wisztorski and Denis Vinatier and Isabelle Fournier and Robert Day and Michel Salzet},
  journal={Proteomics. Clinical applications},
  year={2013},
  volume={7 5-6},
  pages={337-54}
}
PURPOSE Epithelial ovarian carcinogenesis may occur de novo on the surface of ovarian mesothelial epithelial cells or from cells originating in other organs. Foreign Müllerian cell intrusion into the ovarian environment has been hypothesized to explain the latter scenario. In this study, MALDI MS profiling technology was used to provide molecular insights regarding these potentially different mechanisms. EXPERIMENTAL DESIGN Using MALDI MS profiling, the molecular disease signatures were… CONTINUE READING
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