Proteomic Profiling of Bronchoalveolar Lavage Fluid in Critically Ill Patients with Ventilator-Associated Pneumonia

@article{Nguyen2013ProteomicPO,
  title={Proteomic Profiling of Bronchoalveolar Lavage Fluid in Critically Ill Patients with Ventilator-Associated Pneumonia},
  author={E. Nguyen and S. Gharib and Steven J. Palazzo and Y. Chow and D. Goodlett and L. Schnapp},
  journal={PLoS ONE},
  year={2013},
  volume={8}
}
  • E. Nguyen, S. Gharib, +3 authors L. Schnapp
  • Published 2013
  • Medicine
  • PLoS ONE
  • Rationale Ventilator-associated pneumonia (VAP) is a common complication in patients with acute lung injury (ALI) and can lead to increased morbidity and mortality. Identifying protein profiles specific to VAP in bronchoalveolar lavage fluid (BALF) may aid in earlier diagnosis, elucidate mechanisms of disease, and identify putative targets for therapeutic intervention. Methods BALF was obtained from 5 normal subjects and 30 ALI patients: 14 with VAP (VAP+) and 16 without VAP (VAP–). Each sample… CONTINUE READING
    Shotgun MS proteomic analysis of bronchoalveolar lavage fluid in normal subjects.
    15
    Biomarkers in Pneumonia—Beyond Procalcitonin
    11

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 35 REFERENCES
    Ventilator-associated pneumonia
    870