Proteome mining of human follicular fluid reveals a crucial role of complement cascade and key biological pathways in women undergoing in vitro fertilization.

@article{Jarkovsk2010ProteomeMO,
  title={Proteome mining of human follicular fluid reveals a crucial role of complement cascade and key biological pathways in women undergoing in vitro fertilization.},
  author={Karla Jarkovsk{\'a} and Jiřina Mart{\'i}nkov{\'a} and Lucie Liskov{\'a} and Petr Halada and Jir{\'i} Moos and Karel Ře{\vz}{\'a}bek and Suresh Jivan Gadher and Hana Kov{\'a}řov{\'a}},
  journal={Journal of proteome research},
  year={2010},
  volume={9 3},
  pages={1289-301}
}
In vitro fertilization (IVF) is fraught with problems and currently proteomics approaches are being tried out to examine the microenvironment of the follicle in order to assess biological and immunological parameters that may affect its development. Additionally, better understanding of reproductive process may help increase IVF birth rate per embryo transfer and at the same time avoid spontaneous miscarriages or life threatening conditions such as ovarian hyperstimulation syndrome. The primary… CONTINUE READING
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Complement factor H

  • J. P. Atkinson, T. H. Goodship
  • Trends Immunol
  • 2008

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