Proteome map of the normal murine ventricular myocardium.

  title={Proteome map of the normal murine ventricular myocardium.},
  author={L Lam and Jonathan Arthur and Christopher Semsarian},
  volume={7 19},
Cardiovascular disease is the leading cause of morbidity and mortality in developed countries. The underlying mechanisms involved in cardiac dysfunction and heart failure are poorly understood. In this study, 2-DE was utilised to map, for the first time, proteins of normal, nonfailing mouse ventricular tissues to form a basis for future comparative analysis of mouse models with cardiovascular disorders. Proteins were obtained from ventricles of C57BL6 mice, aged 18 wk, and separated by 2-DE. A… CONTINUE READING

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