Proteome and miRNome profiling of microvesicles derived from medulloblastoma cell lines with stem-like properties reveals biomarkers of poor prognosis

@article{Kaid2020ProteomeAM,
  title={Proteome and miRNome profiling of microvesicles derived from medulloblastoma cell lines with stem-like properties reveals biomarkers of poor prognosis},
  author={Carolini Kaid and Amanda Assoni and Marina Marçola and Patr{\'i}cia Semedo-Kuriki and Oswaldo Keith Okamoto},
  journal={Brain Research},
  year={2020},
  volume={1730}
}
Primary central nervous system (CNS) tumors are the most common deadly childhood cancer. Several patients with medulloblastoma experience local or metastatic recurrences after standard treatment, a condition associated with very poor prognosis. Current neuroimaging techniques do not accurately detect residual stem-like medulloblastoma cells promoting tumor relapses. In attempt to identify candidate tumor markers that could be circulating in blood or cerebrospinal (CSF) fluid of patients, we… CONTINUE READING