Proteome analysis of primary neurons and astrocytes from rat cerebellum.

  title={Proteome analysis of primary neurons and astrocytes from rat cerebellum.},
  author={Jae-Won Yang and Regina Rodrigo and Vicente Felipo and Gert Lubec},
  journal={Journal of proteome research},
  volume={4 3},
Neurons and astrocytes are predominant cell types in brain and have distinguished morphological and functional features. Although several proteomics studies were carried out on the brain, work on individual brain cells is limited. Generating individual proteomes of neurons and astrocytes, however, is mandatory to assign protein expression to cell types rather than to tissues. We aimed to provide maps of rat primary neurons and astrocytes using two-dimensional gel electrophoresis with subsequent… CONTINUE READING
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