Proteome analysis of hepatocellular carcinoma by laser capture microdissection.

  title={Proteome analysis of hepatocellular carcinoma by laser capture microdissection.},
  author={Jianhua Ai and Yexiong Tan and Wantao Ying and Yi Min Hong and Shuqing Liu and Meng-chao Wu and Xiaohong Qian and Hong-yang Wang},
  volume={6 2},
Hepatocellular carcinoma (HCC) is one of the most frequent visceral neoplasia worldwide and is a multifactorial and multistage pathogenesis that finally leads to the deregulation of cell homeostasis. Laser capture microdissection (LCM) may allow a more ready identification of differences in protein expression in selected cell types or areas of tissue, and microscopic regions as small as 3-5 microm in diameter can be sampled. Here we applied the LCM to the proteomic study of hepatitis B-related… CONTINUE READING


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