Proteome analysis of body fluids for amyotrophic lateral sclerosis biomarker discovery.

Abstract

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder of motor neurons leading to death of the patients, mostly within 2-5 years after disease onset. The pathomechanism of motor neuron degeneration is only partially understood and therapeutic strategies based on mechanistic insights are largely ineffective. The discovery of… (More)
DOI: 10.1002/prca.201200067

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