Proteome Changes in the Plasma of Myelodysplastic Syndrome Patients with Refractory Anemia with Excess Blasts Subtype 2

@inproceedings{Mjek2014ProteomeCI,
  title={Proteome Changes in the Plasma of Myelodysplastic Syndrome Patients with Refractory Anemia with Excess Blasts Subtype 2},
  author={Pavel M{\'a}jek and Zuzana Riedelov{\'a}-Reicheltov{\'a} and Jiri Suttnar and Klara Pecankova and Jaroslav {\vC}erm{\'a}k and Jan Evangelista Dyr},
  booktitle={Disease markers},
  year={2014}
}
The goal of this study was to explore the plasma proteome of myelodysplastic syndrome (MDS) patients with refractory anemia with excess blasts subtype 2 (RAEB-2) in comparison to healthy controls. 20 plasma samples were separated with 2D electrophoresis and statistically processed with Progenesis SameSpots software. 47 significantly differing (P < 0.05) spots were observed, and 27 different proteins were identified by nano-LC-MS/MS. Mass spectrometry-based relative label-free quantification… CONTINUE READING