Proteolytic selection for protein folding using filamentous bacteriophages.

Abstract

BACKGROUND Filamentous bacteriophages have been used for the selection of folded peptide and protein 'ligands' by binding the phage to 'receptor'-coated solid phase. Here, using proteolysis, we have developed a technique for the selection of folded and stable proteins that is independent of their binding activities. RESULTS When a 21-residue peptide… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.