Proteolytic enzyme activity and Plasmodium falciparum sporogonic development in three species of Anopheles mosquitoes.

If proteolytic enzymes affect the innate vector competence of Anopheles mosquitoes for Plasmodium infections, then mechanistic effects should be most pronounced at the zygote to ookinete developmental transition. Anopheles freeborni, Anopheles gambiae, and Anopheles albimanus exhibit excellent, good, and poor susceptibility to P. falciparum, respectively… CONTINUE READING