Proteolysis in human breast cancer.

  title={Proteolysis in human breast cancer.},
  author={E A Garbett and Michael W Reed and Timothy J Stephenson and Nicola J M Brown},
  journal={Molecular pathology : MP},
  volume={53 2},
BACKGROUND The process of proteolysis is important at several stages of the metastatic cascade. A balance between the expression of the genes encoding endogenous proteinases and inhibitors exists and when the production of proteinases exceeds that of inhibitors proteolysis occurs. AIMS To determine whether differences in the profile and activity of proteinases and inhibitors exist within breast tumour tissue (n = 51), surrounding background breast tissue (n = 43), normal breast tissue from… CONTINUE READING
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The expression of MMPs and TIMPs in human breast cancer tissues and importance of their balance in cancer invasion and metastasis [ abstract ]

  • H Iwata, S Kobayashi, H Iwasw
  • Japanese Journal of Clinical Medicine
  • 1995

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