Proteoglycans from rabbit articular and growth plate cartilage. Ultracentrifugation, gel chromatography, and electron microscopy.

@article{Axelsson1983ProteoglycansFR,
  title={Proteoglycans from rabbit articular and growth plate cartilage. Ultracentrifugation, gel chromatography, and electron microscopy.},
  author={Inge Axelsson and Inna Berman and J. R. Castrej{\'o}n Pita},
  journal={The Journal of biological chemistry},
  year={1983},
  volume={258 14},
  pages={8915-21}
}
Proteoglycans are considered to be important for the mechanical properties of articular cartilage and growth plate and for the regulation of calcification of growth plate. We have used ultracentrifugation, gel chromatography, and electron microscopy to characterize and compare proteoglycans isolated from rabbit articular cartilage, uncalcified growth plate, and calcified cartilage. We found that proteoglycans from articular cartilage were more resistant to extraction than were proteoglycans… CONTINUE READING