Proteoform analysis of lipocalin-type prostaglandin D-synthase from human cerebrospinal fluid by isoelectric focusing and superficially porous liquid chromatography with Fourier transform mass spectrometry.

Abstract

Lipocalin-type prostaglandin D-synthase (L-PGDS) in cerebrospinal fluid contributes to the maturation and maintenance of the CNS. L-PGDS PTMs may contribute to pathobiology of different CNS diseases, but methods to monitor its proteoforms are limited. Herein, we combined off-gel IEF and superficially porous LC (SPLC) with Fourier transform MS to… (More)
DOI: 10.1002/pmic.201300368

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@article{Zhang2014ProteoformAO, title={Proteoform analysis of lipocalin-type prostaglandin D-synthase from human cerebrospinal fluid by isoelectric focusing and superficially porous liquid chromatography with Fourier transform mass spectrometry.}, author={Junmei Zhang and John R. Corbett and Daniel A. Plymire and Benjamin M. Greenberg and Steven M Patrie}, journal={Proteomics}, year={2014}, volume={14 10}, pages={1223-31} }