Proteins mediating DNA loops effectively block transcription

Abstract

Loops are ubiquitous topological elements formed when proteins simultaneously bind to two noncontiguous DNA sites. While a loop-mediating protein may regulate initiation at a promoter, the presence of the protein at the other site may be an obstacle for RNA polymerases (RNAP) transcribing a different gene. To test whether a DNA loop alters the extent to… (More)
DOI: 10.1002/pro.3156

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Cite this paper

@inproceedings{Vrs2017ProteinsMD, title={Proteins mediating DNA loops effectively block transcription}, author={Zsuzsanna V{\"{o}r{\"{o}s and Yan Yan and Daniel T Kovari and Laura Finzi and David Dunlap}, booktitle={Protein science : a publication of the Protein Society}, year={2017} }