Proteins and mechanisms regulating gap-junction assembly, internalization, and degradation.


Gap junctions (GJs) are the only known cellular structures that allow a direct cell-to-cell transfer of signaling molecules by forming densely packed arrays or "plaques" of hydrophilic channels that bridge the apposing membranes of neighboring cells. The crucial role of GJ-mediated intercellular communication (GJIC) for all aspects of multicellular life… (More)
DOI: 10.1152/physiol.00038.2012


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