Proteins, exons and molecular evolution.

@article{Holland1987ProteinsEA,
  title={Proteins, exons and molecular evolution.},
  author={Stephen K. Holland and Colin C. F. Blake},
  journal={Bio Systems},
  year={1987},
  volume={20 2},
  pages={181-206}
}
The discovery of the eukaryotic gene structure has prompted research into the potential relationship between protein structure and function and the corresponding exon/intron patterns. The exon shuffling hypothesis put forward by Gilbert and Blake suggests the encodement of structural and functional protein elements by exons which can recombine to create novel proteins. This provides an explanation for the relatively rapid evolution of proteins from a few primordial molecules. As the number of… CONTINUE READING

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