Proteinases of the mammary gland: developmental regulation in vivo and vectorial secretion in culture.

@article{Talhouk1991ProteinasesOT,
  title={Proteinases of the mammary gland: developmental regulation in vivo and vectorial secretion in culture.},
  author={Rabih S Talhouk and Jennie R. Chin and Elaine N Unemori and Zena Werb and Mina J. Bissell},
  journal={Development},
  year={1991},
  volume={112 2},
  pages={439-49}
}
The extracellular matrix (ECM) is an important regulator of mammary epithelial cell function both in vivo and in culture. Substantial remodeling of ECM accompanies the structural changes in the mammary gland during gestation, lactation and involution. However, little is known about the nature of the enzymes and the processes involved. We have characterized and studied the regulation of cell-associated and secreted mammary gland proteinases active at neutral pH that may be involved in… CONTINUE READING

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Expression of extracellular matrixdegrading proteinases and their inhibitors during involution of the mammary gland of CD - I mice

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1 Excerpt

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