Proteinase-activated receptor-2 activation participates in allergic sensitization to house dust mite allergens in a murine model.


BACKGROUND Many aeroallergens contain proteinase activity and are able to induce allergic sensitization when presented to mucosal surfaces. Some of these allergens activate proteinase-activated receptor-2 (PAR2 ). OBJECTIVE To determine the role of PAR2 activation in a murine house dust mite (HDM) allergy model. METHODS We sensitized and challenged PAR2… (More)
DOI: 10.1111/cea.12185



Citations per Year

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