Protein-tyrosine phosphatases in the vessel wall: differential expression after acute arterial injury.

@article{Wright2000ProteintyrosinePI,
  title={Protein-tyrosine phosphatases in the vessel wall: differential expression after acute arterial injury.},
  author={Matthew B. Wright and Ronald A. Seifert and Daniel F. Bowen-Pope},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2000},
  volume={20 5},
  pages={1189-98}
}
Many protein-tyrosine phosphatases (PTPases) have now been identified, but little is known about PTPase expression and regulation in vascular tissue and in vascular disease. Polymerase chain reaction (PCR) amplification and cDNA fingerprinting of PTPase catalytic domains, combined with random sequencing of PCR product libraries, identified 18 (8 receptor-like and 10 cytosolic) PTPases in the rat carotid artery and revealed differential expression of 5 of these PTPases during neointima formation… CONTINUE READING

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