Protein tyrosine phosphatase activity is necessary for E-cadherin-activated Src signaling.

Abstract

Co-operation between cadherin adhesion molecules and the cytoskeleton is a key aspect of tissue morphogenesis that is mediated by cortical signaling at adhesive junctions. One such signal is the non-receptor tyrosine kinase, Src, which acts in several pathways at epithelial junctions, including E-cadherin signaling itself. We now present two new insights… (More)
DOI: 10.1002/cm.20492

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