Protein turnover forms one of the highest maintenance costs in Lactococcus lactis.

@article{Lahtvee2014ProteinTF,
  title={Protein turnover forms one of the highest maintenance costs in Lactococcus lactis.},
  author={Petri-Jaan Lahtvee and Andrus Seiman and Liisa Arike and Kaarel Adamberg and Raivo Vilu},
  journal={Microbiology},
  year={2014},
  volume={160 Pt 7},
  pages={1501-12}
}
Protein turnover plays an important role in cell metabolism by regulating metabolic fluxes. Furthermore, the energy costs for protein turnover have been estimated to account for up to a third of the total energy production during cell replication and hence may represent a major limiting factor in achieving either higher biomass or production yields. This work aimed to measure the specific growth rate (μ)-dependent abundance and turnover rate of individual proteins, estimate the ATP cost for… CONTINUE READING
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