Protein transfer at the blood cerebrospinal fluid barrier and the quantitation of the humoral immune response within the central nervous system.

@article{Reiber1987ProteinTA,
  title={Protein transfer at the blood cerebrospinal fluid barrier and the quantitation of the humoral immune response within the central nervous system.},
  author={Hansotto Reiber and Klaus Felgenhauer},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={1987},
  volume={163 3},
  pages={319-28}
}
The cerebrospinal fluid (CSF)/serum concentration quotients of albumin and the immunoglobulins G, A and M have been determined for 396 patients with a normal blood CSF barrier function or a pure barrier impairment without a humoral immune response within the central nervous system. The ratios between the concentration quotients of the three immunoglobulins and that of albumin increase in a nonlinear fashion with progressive impairments of the blood CSF barrier, i.e. the molecular size dependent… CONTINUE READING
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