Protein synthesis inhibitors activate glucose transport without increasing plasma membrane glucose transporters in 3T3-L1 adipocytes.

Abstract

In this study, we tested the hypothesis that hexose transport regulation may involve proteins with relatively rapid turnover rates. 3T3-L1 adipocytes, which exhibit 10-fold increases in hexose transport rates within 30 min of the addition of 100 nM insulin, were utilized. Exposure of these cells to 300 microM anisomycin or 500 microM cycloheximide caused a… (More)

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@article{Clancy1991ProteinSI, title={Protein synthesis inhibitors activate glucose transport without increasing plasma membrane glucose transporters in 3T3-L1 adipocytes.}, author={Brian M Clancy and S. A. Harrison and Jane Buxton and M. P. Czech}, journal={The Journal of biological chemistry}, year={1991}, volume={266 16}, pages={10122-30} }