Protein synthesis in pulmonary alveolar macrophages. Source of amino acids for leucyl-tRNA.

@article{Airhart1981ProteinSI,
  title={Protein synthesis in pulmonary alveolar macrophages. Source of amino acids for leucyl-tRNA.},
  author={J A Airhart and Jane A. Arnold and C A Bulman and Robert B. Low},
  journal={Biochimica et biophysica acta},
  year={1981},
  volume={653 1},
  pages={108-17}
}
Extracellular, intracellular and tRNA-bound leucine pools of the adherent pulmonary alveolar macrophage were examined to determine the relationships between them and the precursor for protein synthesis. When cells were cultured in media of various leucine concentrations, the patterns of isotope distribution in intracellular and extracellular leucine did not correlate with the patterns seen in protein-bound leucine. hence, the free leucine pools cannot be used reliably as precursors for… CONTINUE READING