Protein structure computing in the genomic era.

  title={Protein structure computing in the genomic era.},
  author={Torsten Schwede and Alexander V. Diemand and Nicolas Guex and Manuel C. Peitsch},
  journal={Research in microbiology},
  volume={151 2},
Functional analysis of the proteins discovered in fully sequenced genomes represents the next major challenge of life science research. Computational methods play a crucial role in this activity and, among them, comparative protein modelling is of great assistance during the rational design of mutagenesis experiments. Our aim over the last several years has been to further the use of 3-D model structures in this field. Therefore, we have developed a comparative protein modelling environment… CONTINUE READING

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