Protein structure comparison by probability-based matching of secondary structure elements

@article{Shih2003ProteinSC,
  title={Protein structure comparison by probability-based matching of secondary structure elements},
  author={Edward S. C. Shih and Ming-Jing Hwang},
  journal={Bioinformatics},
  year={2003},
  volume={19 6},
  pages={735-41}
}
MOTIVATION Protein structure comparison (PSC) has been used widely in studies of structural and functional genomics. However, PSC is computationally expensive and as a result almost all of the PSC methods currently in use look only for the optimal alignment and ignore many alternative alignments that are statistically significant and that may provide insight into protein evolution or folding. RESULTS We have developed a new PSC method with efficiency to detect potentially viable alternative… CONTINUE READING
Highly Cited
This paper has 29 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Study on fast rough alignment for two-stage protein structure comparison algorithm

Conference, Emerging Information Technology 2005. • 2005
View 8 Excerpts
Highly Influenced

Protein Structure Comparison and Alignment Using Residue Contexts

22nd International Conference on Advanced Information Networking and Applications - Workshops (aina workshops 2008) • 2008
View 1 Excerpt

Heuristic Strategy for Geometric Hashing Based Protein Structure Comparison of Ellipsoidal Representation

2007 IEEE International Conference on Bioinformatics and Biomedicine (BIBM 2007) • 2007
View 2 Excerpts

Similar Papers

Loading similar papers…