Protein stress and stress proteins: implications in aging and disease

  title={Protein stress and stress proteins: implications in aging and disease},
  author={Csaba Sőti and P{\'e}ter Csermely},
  journal={Journal of Biosciences},
Environmantal stress induces damage that activates an adaptive response in any organism. The cellular stress response is based on the induction of cytoprotective proteins, the so called stress or heat shock proteins. The stress response as well as stress proteins are ubiquitous, highly conserved mechanism, and genes, respectively, already present in prokaryotes. Chaperones protect the proteome against conformational damage, promoting the function of protein networks. Protein damage takes place… CONTINUE READING


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