Protein sorting and membrane-mediated interactions

@article{Hanulov2012ProteinSA,
  title={Protein sorting and membrane-mediated interactions},
  author={M{\'a}ria Hanulov{\'a} and Matthias Weiss},
  journal={Biophysical Reviews},
  year={2012},
  volume={4},
  pages={117-124}
}
Sorting of membrane proteins is of vital importance for living cells. Indeed, roughly one-third of a eukaryotic cell’s proteome consists of peripheral and transmembrane proteins. These need to be properly distributed and dynamically maintained at distinct locations in the compartmentalized cell, and one may wonder how proteins determine where, when, and how to travel to reach a specific organelle. While specific binary interactions between proteins have been invoked in explaining the… CONTINUE READING

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