Protein serine/threonine phosphatases: life, death, and sleeping.

  title={Protein serine/threonine phosphatases: life, death, and sleeping.},
  author={Monica Gallego and David M Virshup},
  journal={Current opinion in cell biology},
  volume={17 2},
Protein serine/threonine phosphatases control key biological pathways including early embryonic development, cell proliferation, cell death, circadian rhythm and cancer. Recent studies have provided important insights into how several of the many phosphatase regulators, through their interaction with a conserved phosphatase catalytic subunit, control the activity of critical substrates in these diverse pathways. Recent co-crystal structures provided a major insight into how the diverse protein… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 61 extracted citations

Regulation of TGF-beta signalling by protein phosphatases.

The Biochemical journal • 2010
View 10 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…