Protein sequence redundancy reduction: comparison of various method

@inproceedings{Sikic2010ProteinSR,
  title={Protein sequence redundancy reduction: comparison of various method},
  author={Kresimir Sikic and Oliviero Carugo},
  booktitle={Bioinformation},
  year={2010}
}
Non-redundant protein datasets are of utmost importance in bioinformatics. Constructing such datasets means removing protein sequences that overreach certain similarity thresholds. Several programs such as 'Decrease redundancy', 'cd-hit', 'Pisces', 'BlastClust' and 'SkipRedundant' are available. The issue that we focus on here is to what extent the non-redundant datasets produced by different programs are similar to each other. A systematic comparison of the features and of the outputs of these… CONTINUE READING

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