Protein secretion from Saccharomyces cerevisiae directed by the prepro-alpha-factor leader region.

@article{Zsebo1986ProteinSF,
  title={Protein secretion from Saccharomyces cerevisiae directed by the prepro-alpha-factor leader region.},
  author={Kristina M. Zsebo and Hsieng Sen Lu and J C Fieschko and Leon Goldstein and Judianne Davis and K Duker and S V Suggs and Phillip H. Lai and Grant A. Bitter},
  journal={The Journal of biological chemistry},
  year={1986},
  volume={261 13},
  pages={5858-65}
}
The Saccharomyces cerevisiae secretory process was studied by evaluating secretion efficiency, processing efficiency, and the efficiency of protein folding for hybrid proteins containing the yeast prepro-alpha-factor leader region. Secretion of three proteins, beta-endorphin, calcitonin, and a consensus alpha-interferon (IFN-Con1), were compared in terms of… CONTINUE READING